Designer drugs on the Internet : a phenomenon out-of-control? : The emergence of hallucinogenic drug Bromo-Dragonfly

Copyright Bentham Science PublishersBased on the material available in both the scientific literature and on the web, the present paper provides an updated pharmacological, chemical, toxicological and behavioural overview of Bromo-Dragonfly (1-(8-bromobenzo[1,2- b;4,5-b']difuran-4-yl)-2-aminopropane; 'B-fly'). B-Fly is a powerful, long lasting, LSD-like, hallucinogenic drug, which has been associated with a number of acute intoxications and fatalities in a number of countries. A critical discussion of the potential of misuse of B-fly but also of the methodological limitations, which are intrinsically associated with the analysis of online, non-peer reviewed, material, is presented. It is concluded that the availability of online information on novel psychoactive drugs, such as B-fly, may constitute a public health challenge. Better international collaboration levels may be needed to tackle this novel and fast growing phenomenonPeer reviewe

Promoting innovation and excellence to face the rapid diffusion of Novel Psychoactive Substances (NPS) in the EU : the outcomes of the ReDNet project

Objectives: The recent emergence of new psychoactive compounds (NPS) has raised prominent challenges in the fields of drug policy, substance use research, public health and service provision. The Recreational Drugs European Network (ReDNet) project, funded by the European Commission, was implemented to improve the information stream to young people and professionals about effects/risks of NPS identifying online products and disseminating relevant information through technological tools. Methods: Regular multilingual qualitative assessments of websites, drugs fora and other online resources were carried out using the Google search engine in 8 languages from collaborating countries. These included: the UK, Norway, Belgium, Germany, Hungary, Poland, Italy and Spain. Products were tested and prevention messages were developed and disseminated via technological tools such as interactive websites, SMS alert, social networking (Facebook, Twitter), Multimedia (You Tube), Smartphone applications (iPhone), and virtual learning environments (Second Life). Results: The ReDNet project established itself as the first Europe-wide prevention programme designed for NPS based on the efficacy of novel ICT-based forms of intervention. More than 650 NPS products and combinations were identified; relevant information was disseminated to target population and advice was given to both EU/ international agencies and national policy makers. Conclusions: Web monitoring activities are essential for mapping the diffusion of NPS and the use of technological tools can be successfully incorporated in specific prevention programmes. Furthermore, the involvement of multi-disciplinary international partnerships was and continues to be fundamental for responding to such a prominent challenge.Peer reviewedSubmitted Versio

'Unplugged': a new European school programme against substance abuse

This paper presents the rationale, development and application of 'Unplugged', a new school programme for the prevention of substance abuse, which is based on the comprehensive social influence approach (CSI). The programme was developed, implemented and evaluated by a cross-disciplinary group of experts in the frame of a multi-centre study in seven European countries. The basic curriculum consists of 12 units, which are delivered by class teachers to a target population of 12-14 year-old students. Additional programme components were workshops for the students' parents and debriefing sessions led by class peers. The programme's application was monitored by means of structured report forms. This process monitoring allowed for the analysis of problems in implementation, as well as of participatory aspects. 'Unplugged' is the first comprehensive social influence school curriculum in Europe of which the efficacy has been evaluated in a field trial, and it also constitutes an example of a theory- and evidence-based programme against youths' substance use. This report can provide public health and school decision makers with tools to make an informed choice on these kinds of programmes and to survey their application

Psychoactive drug or mystical incense? : Overview of the online available information on Spice products

The aim of the study was to foster the collection and analysis of data from web pages related to information on the consumption, manufacture and sale of Spice products, a brand name for an herbal smoking blend, sold as legal substitute for cannabis. The Google search engine was used to carry out an 8-language qualitative assessment of information available on Spice products in a sample of about 200 web sites. The level of information elicited included both the users' comments on the effects of the products and the reasons behind their popularity. Users' suggestions on unusual drug combinations not found in the Medline were also identified. This is the first comprehensive and multilingual overview of the online available information on Spice products. The appeal of Spice to online customers was associated with its legal status, lack of detection in biological samples, ease of online access and cannabis-like effects. Spice product descriptions did not typically mention the presence of the powerful synthetic THC receptor agonists that seem to account for the psychoactive effects. Health professionals may need to be aware of the web being a new drug resource for both information and purchase of Spice products.Peer reviewe

Identifying emerging trends in recreational drug use : outcomes from the Psychonaut Web Mapping Project

Copyright 2012 Elsevier B.V., All rights reserved.Background: This paper presents the outcomes of the 2-year European Union funded Psychonaut Web Mapping Project which aimed at developing and implementing an integrated web mapping system to promptly identify and learn about novel psychoactive substances (NPS; "legal highs") through the regular monitoring of the Internet. Methods: More than 200 discussion forums, social media, online shops, websites and other Internet resources (e.g. YouTube, eBay, Google, Google Insight) have been extensively and regularly monitored in 7 European countries (UK, Finland, Norway, Belgium, Germany, Italy and Spain) for emerging trends of NPS throughout the period of the study. Results: Key online resources have been identified as "leading edge" which have provided accurate and timely information on novel emerging compounds. In total more than 400 substances/products have been recorded. NPS have been noted online before reaching wider audiences. Discussion: Although a high number of novel psychoactive substances have been identified in the 2-year duration of the project, not all have become trends that needed public health response. Conversely, new recreational drug phenomena such as "spice drugs," mephedrone and naphyrone were all identified as emerging trends in forums and websites. In addition, it has been possible for the first time to collate detailed information on these and several more compounds even though no or limited scientific publications were available. It is therefore recommended that these monitoring activities are to be continued, that more countries, researchers and health professionals are involved, and that the findings are widely shared with all the relevant agencies, health professionals and future research projects. Implications, advantages and limitations of using the Internet as primary source for identifying emerging trends are also discussedPeer reviewe

Az elektronikus prevenció lehetőségei az új (szintetikus) drogok használatának megelőzésében : a Rekreációs Drogok Európai Hálózatának (Recreational Drugs European Network) bemutatása

Peer reviewe

New psychoactive substancesthe youth and professionals informational needs

(translated from Polish) The study conducted in the frame of the RedNet project among health professionals dealing with drug users (N=124) and youth population (N=716) was aimed at assessment of the level of knowledge about new psychoactive substances (NPS), informational needs on NPS and preferred method for the dissemination of information. Data collected in Poland showed that youth rated their knowledge on NPS higher than health professionals as approximately 25% of young respondents and 5% of health professionals reported that their knowledge on NPS is “very good”. Moreover, approximately 90% of young people and 60% of health professionals heard/read about or had known somebody who tried Salvia divinorum, Spice and mephedrone. Most of the professionals (98%) and more than half young people (59%) would like to receive up-to-date information on NPS. For both groups of respondents following information were most often perceived as important in getting an understanding/knowledge on NSP: desired psychoactive effects, adverse side effects, modalities of use and key points/overview. In general, health professional rated importance of particular topics higher than young people. Preferred method of delivery information on NPS for both groups of respondents were: e-mail and Internet. More health professionals than young respondents favoured electronic newsletter, but more young people preferred Facebook as the method of delivery information on NPS.Peer reviewe

Phenomenon of new drugs on the internet: The case of ketamine derivative methoxetamine. Human Psychopharmacology: Clinical and Experimental,

On the basis of the material available both in the scientific literature and on the web, this paper aims to provide a pharmacological, chemical and behavioural overview of the novel compound methoxetamine. This is a dissociative drug related to ketamine, with a much longer duration of action and intensity of effects. A critical discussion of the availability of information on the web of methoxetamine as a new recreational trend is here provided. Those methodological limitations, which are intrinsically associated with the analysis of online, non-peer reviewed, material, are here discussed as well. It is concluded that the online availability of information on novel psychoactive drugs, such as methoxethanine, may constitute a pressing public health challenge. Better international collaboration levels and novel forms of intervention are necessary to tackle this fast-growing phenomenon